MyBioSource.com's FMOD antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The FMOD antibody was generated using Fibromodulin, and Fmod as the antigen and it reacts with Human, Mouse, and Rat.
Description
Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants